Antenatal origins of reduced lung function-but not asthma?
نویسندگان
چکیده
منابع مشابه
Serum levels of IL-17A increase in Asthma but not in accordance with Serum level of IgE and Asthma Severity
Background and Aims: Recent evidence suggests that T helper (Th) 17 cells are involved in the emergence of asthma. Th17 cells have a key role in inducing inflammation in asthmatic airways thus Interleukin (IL)-17A, the main cytokine of Th17, contributes to airways inflammation. Materials and Methods: We evaluated the level of IL-17A and total immunoglobulin E (IgE) in sera of 100 asthmatic p...
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Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...
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BACKGROUND In asthma, mechanisms contributing to chronicity remain to be determined. Recent models of sensitisation with prolonged airway allergen challenges reproduce typical features of chronic asthma. However, the interplay between inflammation, structural changes and lung function is poorly understood. This study was performed to delineate functional, structural and immunological airway cha...
متن کاملPerinatal lung function and invasive antenatal procedures.
BACKGROUND Second trimester amniocentesis has been associated with an excess of perinatal lung function abnormalities. Early amniocentesis might have a similar adverse effect, as could other invasive investigations carried out in the first trimester. METHODS Plethysmographic measurements of thoracic gas volume (TGV) and airway resistance (Raw), from which specific conductance (sGaw) was calcu...
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P rogressive decline in lung function in asthma has been well recognised but not fully explained. For example, in a Danish population study (the Copenhagen City Heart Study), three measurements of forced expiratory volume in one second (FEV1) were made over 15 yrs in 17,506 subjects, including 1,095 with asthma [1]. Asthmatics showed a decline in FEV1 of 38 mL?yr compared with 22 mL?yr in norma...
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ژورنال
عنوان ژورنال: Respirology
سال: 2016
ISSN: 1323-7799
DOI: 10.1111/resp.12794